Drugs comprising in association at least one immunotoxin and at least one monovalent carboxylic ionophore

Abstract

The present invention relates to drugs characterized in that they comprise, in association, at least one immunotoxin and at least one monovalent carboxylic ionophore.

We claim: 
     
       1. A cytotoxic composition comprising a cytotoxic amount of an immunotoxin and a potentiating amount of a monovalent carboxylic ionophore selected from the group consisting of monensin, nigericin, grisorixin and lasalocide, said immunotoxin comprising the A chain of ricin covalently bonded to an antibody, or antibody fragment directed against an antigen carried by the cells to be destroyed. 
     
     
       2. The cytotoxic composition of claim 1 which is in the form suitable for administration via injection.