Wound-healing preparations

Abstract

A wound-healing preparation is composed of 50-90 wt. % of a sugar, 0.5-10 wt. % of povidone-iodine, and 1-20 wt. % of water. A buffer is also contained in an amount sufficient to adjust the pH of the preparation to 3.5-6. Preferably, the preparation may additionally contain 0.1-5 wt. % of an agent for imparting an appropriate consistency and stability, which is selected from polysaccharides and derivatives thereof.

We claim: 
     
       1. A wound-healing preparation, comprising: 50-90 wt.% of a sugar, 0.5-10 wt.% of povidone-iodine, 1-20 wt.% of water and a buffer selected from the group consisting of lactate buffer, citrate buffer, phosphate buffer and potassium hydrogen phthalate buffer in an amount sufficient to adjust the pH of the preparation to 3.5-6. 
     
     
       2. The wound-healing preparation of claim 1, which preparation further comprises from 0.1 to 5 wt% of an agent which imparts consistency and stability to the preparation, said agent being a polysaccharide or derivative thereof. 
     
     
       3. The wound-healing preparation of claim 1, wherein the amount of said sugar ingredient present ranges from 60-80% by weight. 
     
     
       4. The wound-healing preparation of claim 1, wherein the amount of said water in the composition ranges from 1-15% by weight. 
     
     
       5. The wound-healing preparation of claim 2, wherein said polysaccharide or derivative thereof is dextrin, gum arabic, pullulan, chondroitin sulfate, methylcellulose or sodium carboxymethylcellulose. 
     
     
       6. The wound-healing preparation of claim 2, wherein the amount of said polysaccharide or derivative thereof in the composition ranges from 0.1 to 3 wt.%. 
     
     
       7. The wound-healing preparation of claim 2, wherein said composition contains a solubilizing ingredient which is potassium iodide, sodium iodide or glycerin. 
     
     
       8. The wound-healing preparation of claim 2, wherein said composition further comprises at least one excipient which is a glycol, a glycerin, polyoxyethylene-hardened castor oil or polyoxyethylene-polyoxyropylene block polymer. 
     
     
       9. The wound-healing preparation of claim 1, wherein said sugar is a non-reducing sugar selected from the group consisting of sucrose, glucose, dextrose, honey and molasses.