US4867164AExpiredUtility

Neurocybernetic prosthesis

97
Assignee: ZABARA JACOBPriority: Sep 14, 1983Filed: Oct 26, 1987Granted: Sep 19, 1989
Est. expirySep 14, 2003(expired)· nominal 20-yr term from priority
Inventors:Jacob Zabara
A61N 1/36157A61N 1/36167A61N 1/36067A61N 1/36053A61N 1/36064A61N 1/36082A61N 1/372
97
PatentIndex Score
730
Cited by
11
References
9
Claims

Abstract

A neurocybernetic prosthesis for controlling or preventing epileptic seizures and other motor disorders includes a pulse generator which generates electrical pulses having a frequency of between 30 and 300 cycles per second, a pulse duration of between 0.3 and 1 millisecond and a constant current of between 1 and 20 milliamperes. The generator is enclosed in an epoxy-titanium shell and is implanted in the body, preferably in the axilla. Electrode leads pass from the generator through a subcutaneous tunnel and terminate in an electrode patch on the vagus nerve. Provisions are made for varying the electrical signal from the generator after it has been implanted to "tune" the same to the patient. The prosthesis may be designed to be turned on manually when the patient senses the imminence of a convulsion. Alternatively, sensors may be provided for determining changes in the values of state parameters such as electroencephalographic waves which precede a convulsion. The pulse generator can then be turned on automatically in response to the sensors.

Claims

exact text as granted — not AI-modified
I claim: 
     
       1. A method of controlling or preventing involuntary movements such as caused by epileptic seizures, cerebral palsy, Parkinson's disease, spasticity, motor disorders and the like comprising applying a pulsed electrical signal to the vagus nerve in such a way as to avoid any substantial slowing of the heart rate, said signal being applied repeatedly over a period of time to thereby prevent or control such movement. 
     
     
       2. The method of claim 1 wherein the electrical signal has a pulse frequency of approximately between 30 and 300 cycles per second and wherein each pulse has a duration of between 0.3 and 1 millisecond and substantially constant current of between approximately 1 and 20 milliamperes. 
     
     
       3. The method of claim 1 wherein the signal is applied utilizing a plurality of electrodes. 
     
     
       4. The method of claim 3 wherein there is a negative electrode and a positive electrode and wherein the negative electrode is applied proximal to the brain and the positive electrode is applied distal thereto. 
     
     
       5. The method of claim 3 wherein there is a negative electrode and a positive electrode and wherein the negative electrode is placed in the vicinity of the vagus nerve and the positive electrode is applied to a remote part of the body. 
     
     
       6. A method of controlling or preventing involuntary movements such as caused by epileptic seizures, cerebral palsy, Parkinson's disease, spasticity, motor disorders and the like comprising applying a pulsed electrical signal to the vagus nerve at a point below the inferior cardiac nerve, said signal having a pulse frequency of approximately between 30 and 300 cycles per second wherein each pulse has a duration of between 0.3 and 1 millisecond and substantially constant current of between approximately 1 and 20 milliamperes, and said signal being applied repeatedly over a period of time to thereby prevent or control such movement. 
     
     
       7. A method of controlling or preventing involuntary movements such as caused by epileptic seizures, cerebral palsy, Parkinson's disease, spasticity, motor disorders and the like comprising applying a pulsed electrical signal to the vagus nerve at a point below the inferior cardiac nerve, said signal being applied utilizing a plurality of electrodes and further being applied repeatedly over a period of time to thereby prevent or control such movement. 
     
     
       8. The method of claim 7 wherein there is a negative electrode and a positive electrode and wherein the negative electrode is applied proximal to the brain and the positive electrode is applied distal thereto. 
     
     
       9. The method of claim 7 wherein there is a negative electrode and a positive electrode and wherein the negative electrode is placed in the vicinity of the vagus nerve and the positive electrode is applied to a remote part of the body.

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