US5008452AExpiredUtility

Aminoethyl oximes

23
Assignee: DUPHAR INT RESPriority: Apr 5, 1967Filed: Dec 20, 1989Granted: Apr 16, 1991
Est. expiryApr 5, 1987(expired)· nominal 20-yr term from priority
C07D 327/08C07D 215/12C07D 319/18C07C 271/16C07D 317/58C07C 2603/18
23
PatentIndex Score
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Cited by
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References
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Claims

Abstract

The compound of the formula ##STR1## wherein R 6 is H or Halo and R is alkoxy or alkyl thio, having, with (CH 2 )n a total of up to eight carbon atoms are described as having antidepressant as well as sedative activity.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
       1. A compound of the formula: ##STR12## or salts thereof with pharmaceutically acceptable acids wherein R 3  is selected from the group consisting of alkoxy alkyl and alkylthio alkyl each having up to eight carbon atoms, and R 6  is a hydrogen atom or a halogen atom, wherein when R 6  is a chlorine atom, R 3  cannot be ethoxybutyl, methoxypentyl, or ethoxypentyl, and when R 6  is a bromine atom, R 3  cannot be methoxybutyl. 
     
     
       2. As a compound of claim 1 O-(2-amino-ethyl)-2-n.propyloxyacetophenone oxim and salts thereof with pharmaceutically acceptable acids. 
     
     
       3. As a compound of claim 1 O-(2-amino-ethyl)-2-n.propylthioacetophenone oxim and salts thereof with pharmaceutically acceptable acids. 
     
     
       4. The compound of claim 1 wherein R 3  is alkoxyalkyl. 
     
     
       5. The compound of claim 1 wherein R 6  is a halogen atom. 
     
     
       6. The compound of claim 4 wherein R 6  is a halogen atom.

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