US5026539AExpiredUtility
Anticaries dentifrice
Est. expiryMar 28, 2009(expired)· nominal 20-yr term from priority
A61K 8/362A61Q 11/00A61K 8/365
55
PatentIndex Score
16
Cited by
16
References
9
Claims
Abstract
An anti-caries composition has a source of hydrogen citrate ions, preferably an alkali metal hydrogen citrate salt, an oxalate salt and an orally acceptable excipient, and optionally further comprises an ionic fluorine-containing compound. The composition may be in the form of dentifrice when silica is the preferred abrasive, or a mouthwash.
Claims
exact text as granted — not AI-modifiedI claim:
1. An oral hygiene composition in the form of a non-fluoride dentifrice, comprising: (a) greater than 0 to 10% by weight of a source of hydrogen citrate ions; (b) greater than 0 to 7% by weight of an oxalate salt; (c) an orally acceptable excipient; and (d) a dentally acceptable abrasive; the composition having a pH of from 4 to 7 and containing no fluoride anti-caries agent.
2. A dentifrice according to claim 1 wherein the source of hydrogen citrate ions is a soluble alkali metal salt.
3. A dentifrice according to claim 2 wherein the salt is a hydrogen citrate salt.
4. A dentifrice according to claim 1 wherein the source of hydrogen citrate ions is present in an amount of from 0.025 to 10% by weight of the composition.
5. A dentifrice according to claim 1 wherein the oxalate salt is an alkali metal oxalate or an alkaline earth metal oxalate, or a combination thereof.
6. A dentifrice according to claim 1 wherein the oxalate salt is present in an amount of from 0.0025 to 7% by weight of the composition.
7. A dentifrice according to claim 1 wherein the abrasive is selected from the group consisting of dicalcium phosphate, calcium pyrophosphates, alumina, aluminium hydroxide, pumice, plastics particles, zinc orthophosphate and silica.
8. A method of preventing or treating caries which method comprises the application to a subject of an effective amount of a dentifrice of claim 1 to the oral cavity.
9. A dentifrice according to claim 1, wherein said abrasive is a silica abrasive.Cited by (0)
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