US5096808AExpiredUtility

Method and kit for detecting human exposure to genotoxic agents

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Assignee: US HEALTHPriority: Sep 23, 1985Filed: Dec 27, 1988Granted: Mar 17, 1992
Est. expirySep 23, 2005(expired)· nominal 20-yr term from priority
Inventors:Curtis C. Harris
G01N 33/575Y10S436/822Y10S436/813C12Q 1/68Y10S436/815G01N 33/5308
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PatentIndex Score
3
Cited by
16
References
2
Claims

Abstract

The present invention discloses a method and a kit for monitoring human exposure to genotoxic agents. The method comprises an immunoassay for detecting in human serum specific antibodies against DNA adducted to an agent suspected of being genotoxic. A kit comprising various components for performing the assay is also disclosed.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
       1. A method for detecting human exposure to genotoxic agents comprising: obtaining a sample of human serum;   detecting the presence of antibodies specific to DNA-adducts of polycyclic aromatic hydrocarbons;   correlating the presence of said antibodies to current or past exposure to genotoxic agents.   
     
     
       2. A method for detecting human exposure to genotoxic agents comprising: obtaining a sample of human serum;   detecting the presence of antibodies specific to DNA-adducts of 7,12-dimethylbenzanthracene;   correlating the presence of said antibodies to current or past exposure of genotoxic agents.

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