US5130247AExpiredUtility

Expression of fusion protein of HIV envelope and HBsAG

Assignee: MERCK & CO INCPriority: Sep 19, 1989Filed: Sep 19, 1989Granted: Jul 14, 1992

Est. expirySep 19, 2009(expired)· nominal 20-yr term from priority

Inventors:Peter J. Kniskern Arpi Hagopian Pamela D. Burke

A61K 39/00C07K 14/005C07K 2319/00C07K 2319/02C07K 2319/735C12N 2730/10122C12N 2740/16222

PatentIndex Score

Cited by

References

Claims

Abstract

The present invention relates to recombinant fusion polypeptides of HIV envelope and HBsAg, suitable as vaccines against AIDS and/or ARC and hepatitis, as well as immunogens for inducting antibodies for passive protection or treatment of AIDS and/or ARC.

Claims

exact text as granted — not AI-modified

What is claimed is: 
     
       1. The gene coding for RP135/HBsAg. 
     
     
       2. A vector containing the gene coding for RP135/HBsAg. 
     
     
       3. A eukaryotic expression system for the synthesis of RP135/HBsAg in cells in vitro. 
     
     
       4. A yeast expression system for the synthesis of RP135/HBsAg.

Cited by (0)

No later patents cite this yet.

References (0)

No backward citations on record.