Antimicrobial dispersion composition

Abstract

An antimicrobial composition comprises a clathrate compound containing a water-soluble microbicide, and a dispersion medium. For example, the composition may comprise of a clathrate compound containing a water-soluble microbicide and having a particle size of 200 mesh at maximum, said clathrate compound being formed of 5-chloro-2-methyl-4-isothiazoline-3-one and at least one polymolecular host compound selected from the group consisting of 1, 1-di (2,4-dimethylphenyl)-2-propyne-1-ol; 1,1,6,6-tetra(2,4-dimethylphenyl)-2,4-hexadiyne-1,6-diol; 1,1-bis(4-hydroxyphenyl)cyclohexane; N,N,N',N'-tetra(cyclohexyl)-[1,1'biphenyl]-2,2'-dicarboxyamide; 2,2'-methylenebis(4-chlorophenol), deoxycholic acid; and 2,5-di-tert-butylhydroquinone and a dispersion medium.

What is claimed is: 
     
       1. An antimicrobial dispersion composition comprising: a clathrate compound containing a water-soluble microbicide and having a particle size of 200 mesh at maximum, said clathrate compound being formed of 5-chloro-2-methyl-4-isothiazoline-3-one and at least one polymolecular host compound selected from the group consisting of 1,1,6,6-tetra(2,4-dimethylphenyl)-2,4-hexadiyne-1,6-diol; 1,1-bis(4-hydroxyphenyl)cyclohexane; N,N,N',N'-tetra(cyclohexyl)-[1,1'-biphenyl]-2,2'-dicarboxyamide; 2,2'-methylenebis(4-chlorophenol), deoxycholic acid; and 2,5-di-tert-butylhydroquinone; and   water for retaining the clathrate compound with a particle size of 200 mesh at maximum to be equally dispersed therein, said clathrate compound being retained in the water at 10-50 wt. % so that the clathrate compound is stably retained in the water without decomposition of the microbicide.   
     
     
       2. An antimicrobial composition as set forth in claim 1, wherein said clathrate compound comprises 10 to 40% by weight of said microbicide and 60 to 90% by weight of said host compound. 
     
     
       3. An antimicrobial composition as set forth in claim 1, further containing a sedimentation inhibitor of high molecular weight or a surface active agent. 
     
     
       4. An antimicrobial dispersion composition comprising: a clathrate compound containing a water-soluble microbicide and having a particle size of 200 mesh at maximum, said clathrate compound being formed of 5-chloro-2-methyl-4-isothiazoline-3-one and at least one polymolecular host compound selected from the group consisting of 1,1,6,6-tetra(2,4-dimethylphenyl)-2,4-hexadiyne-1,6-diol; 1,1-bis(4-hydroxyphenyl)cyclohexane; N,N,N',N'-tetra(cyclohexyl)-[1,1'-biphenyl]-2,2'-dicarboxyamide; 2,2'-methylenebis(4-chlorophenol), deoxycholic acid; and 2,5-di-tert-butylhydroquinone; and   an organic dispersion medium for retaining the clathrate compound with a particle size of 200 mesh at maximum to be equally dispersed therein, said clathrate compound being retained in the dispersion medium at 10-15 wt. % so that the clathrate compound is stably retained in the dispersion medium without decomposition of the microbicide, said organic dispersion medium being at least one member selected from the group consisting of alcohols, liquid paraffin, xylene, vegetable oils, terpenes, and surface active agents.   
     
     
       5. An antimicrobial composition as set forth in claim 4, further containing a sedimentation inhibitor of high molecular weight or a dispersing agent.