US5262174AExpiredUtilityPatentIndex 63
Anti-viral compositions
Est. expiryJul 27, 2003(expired)· nominal 20-yr term from priority
Inventors:HORROBIN DAVID F
A61K 31/70A61K 33/14A61K 38/21A61K 31/19A61K 31/505
63
PatentIndex Score
3
Cited by
15
References
9
Claims
Abstract
The treatment of viral infections with a lithium salt and one of cytarabine or idoxuridine.
Claims
exact text as granted — not AI-modifiedI claim:
1. A pharmaceutical composition comprising as active ingredients an effective synergistic amount of at least one physiologically acceptable lithium salt together with an anti-virally effective amount of at least one anti-viral nucleoside analog.
2. A composition as claimed in claim 1 wherein said lithium salt is selected from the group consisting of lithium chloride, lithium succinate, lithium citrate, lithium acetylsalicylate and lithium orotate.
3. A composition as claimed in claim 1 containing from 0.01 to 30% by weight of lithium ions.
4. A composition as claimed in claim 1 wherein said anti-viral nucleoside analog is selected from the group consisting of cytarabine and idoxuridine.
5. A composition as claimed in claim 1 containing from 0.2 to 10% by weight of said anti-viral nucleoside analog.
6. A method for the treatment of a viral infection in a human or warm-blooded animal subject which comprises conjointly administering to said subject an effective synergistic amount of at least one physiologically acceptable lithium salt together with an anti-virally effective amount of at least one anti-viral nucleoside analog.
7. A method as claimed in claim 6 wherein said lithium salt is selected from the group consisting of lithium chloride, lithium succinate, lithium citrate, lithium acetysalicylate and lithium orotate.
8. A method as claimed in claim 6 wherein said anti-viral nucleoside analog is selected from the group consisting of cytarabine and idoxuridine.
9. A method as claimed in claim 6 wherein said lithium salt and said anti-viral nucleoside analog are topically administered to herpes lesions.Cited by (0)
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