P
US5262174AExpiredUtilityPatentIndex 63

Anti-viral compositions

Assignee: EFAMOL LTDPriority: Jul 27, 1983Filed: Jul 18, 1991Granted: Nov 16, 1993
Est. expiryJul 27, 2003(expired)· nominal 20-yr term from priority
Inventors:HORROBIN DAVID F
A61K 31/70A61K 33/14A61K 38/21A61K 31/19A61K 31/505
63
PatentIndex Score
3
Cited by
15
References
9
Claims

Abstract

The treatment of viral infections with a lithium salt and one of cytarabine or idoxuridine.

Claims

exact text as granted — not AI-modified
I claim: 
     
       1. A pharmaceutical composition comprising as active ingredients an effective synergistic amount of at least one physiologically acceptable lithium salt together with an anti-virally effective amount of at least one anti-viral nucleoside analog. 
     
     
       2. A composition as claimed in claim 1 wherein said lithium salt is selected from the group consisting of lithium chloride, lithium succinate, lithium citrate, lithium acetylsalicylate and lithium orotate. 
     
     
       3. A composition as claimed in claim 1 containing from 0.01 to 30% by weight of lithium ions. 
     
     
       4. A composition as claimed in claim 1 wherein said anti-viral nucleoside analog is selected from the group consisting of cytarabine and idoxuridine. 
     
     
       5. A composition as claimed in claim 1 containing from 0.2 to 10% by weight of said anti-viral nucleoside analog. 
     
     
       6. A method for the treatment of a viral infection in a human or warm-blooded animal subject which comprises conjointly administering to said subject an effective synergistic amount of at least one physiologically acceptable lithium salt together with an anti-virally effective amount of at least one anti-viral nucleoside analog. 
     
     
       7. A method as claimed in claim 6 wherein said lithium salt is selected from the group consisting of lithium chloride, lithium succinate, lithium citrate, lithium acetysalicylate and lithium orotate. 
     
     
       8. A method as claimed in claim 6 wherein said anti-viral nucleoside analog is selected from the group consisting of cytarabine and idoxuridine. 
     
     
       9. A method as claimed in claim 6 wherein said lithium salt and said anti-viral nucleoside analog are topically administered to herpes lesions.

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