US5362905AExpiredUtility

Process for the preparation of L-5-(2-acetoxy-propionylamino)-2,4,6-triiodo-isophthalic acid dichloride

Assignee: ZAMBON SPAPriority: Oct 27, 1992Filed: Oct 22, 1993Granted: Nov 8, 1994

Est. expiryOct 27, 2012(expired)· nominal 20-yr term from priority

Inventors:Marco Villa Maurizio Paiocchi Aldo Di Caterino

B01J 27/10B01J 27/138C07C 231/02

PatentIndex Score

Cited by

References

Claims

Abstract

An improvement to a process for the preparation of L-5-(2-acetoxy-propionylamino)-2,4,6-triiodo-isophthalic acid dichloride by reacting 5-amino-2,4,6-triiodo-isophthalic acid dichloride with L-2-acetoxy-propionyl-chloride, is described.

Claims

exact text as granted — not AI-modified

What we claim is: 
     
       1. In a process for the preparation of L-5-(2-acetoxy-propionylamino)-2,4,6-triiodo-isophthalic acid dichloride by reacting 5-amino-2,4,6-triiodo-isophthalic acid dichloride with L-2-acetoxy-propionyl-chloride, the improvement consisting in operating in the presence of a Lewis acid. 
     
     
       2. A process according to claim 1 wherein the Lewis acid is used in catalytic amounts. 
     
     
       3. A process according to claim 1 or 2 wherein the Lewis acid is a &#34;border line&#34; acid. 
     
     
       4. A process according to claim 1 or 2 wherein the Lewis acid is selected from the group consisting of zinc chloride, aluminum chloride and stannous chloride.

Cited by (0)

No later patents cite this yet.

References (0)

No backward citations on record.