Antiphlogistic analgesic plaster

Abstract

An antiphlogistic analgesic plaster which comprises as essential ingredients: (a) at least one nonsteroidal antiphlogistic analgesic drug selected from among ketoprofen, flurbiprofen, loxoprofen, ketorolac and ester derivatives or salts thereof, (b) a solubilizer comprising a combination of a rosin ester derivative with l-menthol, (e) a styrene/isoprene/styrene block copolymer employed as a base polymer, (d) a softener, and (e) a backing comprising a polyester cloth.

We claim: 
     
       1. An antiphlogistic analgesic plaster consisting essentially of: (a) a nonsteroidal antiphlogistic analgesic drug selected from the group consisting of ketoprofen, flurbiprofen, loxoprofen, ketorolac, ester derivatives salts thereof, and mixtures thereof;   (b) a solubilizer comprising a combination of a rosin ester derivative with l-menthol;   (c) a styrene/isoprene/styrene block copolymer employed as a base polymer;   (d) a softener selected from the group consisting of oils, olefinic acids, and liquid paraffin; and   (e) a backing comprising a polyester cloth, the nonsteroidal antiphlogistic analgesic drug, rosin ester derivative, l-menthol, styrene/isoprene/styrene block copolymer and softener being present in respective mixing ratios by weight of from 0.5 to 10.0%, from 5.0 to 70.0%, from 0.5 to 15.0%, from 5.0 to 40.0% and from 10.0 to 75.0% in this order, the amounts of all said ingredients totalling 100% by weight,   the nonsteroidal antiphlogistic analgesic drug, rosin ester derivative and l-menthol being present in a mixing ratio of 1.0:3.0-11.0:1.0-4.0.   
     
     
       2. The plaster according to claim 1 which contains 7 parts of said rosin ester derivative, 3 parts of l-menthol and 1 part of ketoprofen. 
     
     
       3. The plaster according to claim 1 which contains 8 parts of said rosin ester derivative, 1.2 parts of l-menthol and 1 part of flurbiprofen. 
     
     
       4. The plaster according to claim 1 which contains 8 parts of said rosin ester derivative, 3 parts of l-menthol and 1 part of loxoprofen. 
     
     
       5. The plaster according to claim 1 which contains 9 parts of said rosin ester derivative, 2.5 parts of l-menthol and 1 part of ketorolac.