US5496850AExpiredUtility

Antimetastasis agent of malignant tumors

55
Assignee: TORAY INDUSTRIESPriority: Apr 11, 1991Filed: Oct 9, 1992Granted: Mar 5, 1996
Est. expiryApr 11, 2011(expired)· nominal 20-yr term from priority
A61K 31/557C07D 307/93
55
PatentIndex Score
20
Cited by
8
References
2
Claims

Abstract

An agent which is chemically stable, which prominently inhibits metastasis of malignant tumor and which is safe is disclosed. The antimetastasis agent of malignant tumors according to the present invention comprises as an effective ingredient beraprost or a pharmaceutically acceptable salt thereof.

Claims

exact text as granted — not AI-modified
We claim: 
     
       1. A method inhibiting a metastasis of a malignant tumor in a patient, the method comprising: administering to said patient an effective metastasis inhibiting amount of beraprost, or a stereoisomer thereof;   provided that said patient is selected from the group consisting of a human, a monkey, a dog and a mouse, and that said patient is suffering from said malignant tumor; and   provided that said malignant tumor is selected from the group consisting of a melanoma, lung cancer, stomach cancer, liver cancer, breast cancer, colon cancer, brain cancer, a neck cancer and a head cancer.   
     
     
       2. A method for inhibiting metastasis of a malignant tumor comprising administering an effective amount of beraprost to a patient suffering from the malignant tumor.

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