US5512301AExpiredUtility

Collagen-containing sponges as drug delivery compositions for proteins

89
Assignee: AMGEN INCPriority: May 1, 1992Filed: Nov 30, 1994Granted: Apr 30, 1996
Est. expiryMay 1, 2012(expired)· nominal 20-yr term from priority
Inventors:Suk-Zu SongAndrew Morawiecki
A61L 15/32A61L 15/325A61L 15/425A61L 15/44Y10S128/08A61L 2300/414A61L 15/225A61K 9/2063
89
PatentIndex Score
173
Cited by
42
References
3
Claims

Abstract

Collagen-containing sponges comprising an absorbable gelatin sponge, collagen, and an active ingredient are disclosed as are methods of enhancing wound healing of external and internal wounds using such sponges.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
       1. A collagen-containing sponge comprising an absorbable crosslinked gelatin sponge, soluble collagen, and a therapeutically active amount of PDGF. 
     
     
       2. A method of enhancing wound healing of an epidermal wound comprising administration of a wound healing effective amount of an active ingredient via a collagen sponge comprising an absorbable crosslinked gelatin sponge, soluble collagen, and a therapeutically active amount of said active ingredient. 
     
     
       3. A method of enhancing wound healing of an internal wound comprising administration of a wound healing effective amount of an active ingredient via a collagen sponge comprising an absorbable crosslinked gelatin sponge, soluble collagen, and a therapeutically active amount of said active ingredient.

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