US5523322AExpiredUtilityPatentIndex 54

Method for inhibiting blood-platelet aggregration with β-naphthoquinone compounds

Assignee: ROUSSEL UCLAFPriority: Jul 2, 1993Filed: Jun 30, 1994Granted: Jun 4, 1996

Est. expiryJul 2, 2013(expired)· nominal 20-yr term from priority

Inventors:BLACHE DENIS BLOY CHRISTIAN HERCELIN BERNARD

A61P 7/02A61K 31/175A61K 31/165A61P 7/04A61K 31/12

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Abstract

A method of inhibiting blood-platelet aggregation in warm-blooded animals comprising administering to warm-blooded animals a blood-platelet aggregation inhibiting effective amount of a compound selected from the group consisting of a compound of the formula ##STR1## wherein R is selected from the group consisting of --NH--CO--NH 2 , --NH--CO--CH 3 , --OH and their non-toxic, pharmaceutically acceptable acid addition salts.

Claims

exact text as granted — not AI-modified

What is claimed is: 
     
       1. A-method of inhibiting blood-platelet aggregation in warm-blooded animals comprising administering to warm-blooded animals in need thereof a blood-platelet aggregation inhibiting effective amount of a compound selected from the group consisting of a compound of the formula ##STR3## wherein R is selected from the group consisting of --NH--CO--NH 2 , --NH--CO--CH 3 , --OH and their non-toxic, pharmaceutically acceptable acid addition salts. 
     
     
       2. The method of claim 1 wherein R is --NH--CO--NH 2 . 
     
     
       3. The method of claim 1 wherein R is --NH--CO--CH 3 . 
     
     
       4. The method of claim 1 wherein R is --OH. 
     
     
       5. The method of claim 1 wherein the compound is 1,2-naphthoquinone-2-semicarbazone.

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