Sterile topical anesthetic gel

Abstract

The present invention provides a topical anesthetic gel composition, comprising: (a) one or more topical anesthetic agents; (b) an adrenergic sympathomimetic compound; and (c) a pharmaceutical gel component. The present invention also provides a topical anesthetic gel composition, comprising: (a) tetracaine HCl, wherein said tetracaine HCl is contained in said composition in an amount of from about 0.01% to about 1.0% by weight, based upon the total weight of said composition; (b) epinephrine HCl topical solution, wherein said epinephrine HCl is contained in said composition in an amount of from about 0.04% to about 0.1% by weight, based upon the total weight of said composition; (c) cocaine HCl, wherein said cocaine HCl is contained in said composition in an amount of from about 3.0% to about 12.0% by weight, based upon the total weight of said composition; and (d) GELFOAM TM , wherein said Gelfoam TM is contained in said composition in an amount of from about 6.0% to about 9.0% by weight, based upon the total weight of said composition. Further provided are other topical anesthetic compositions.

What is claimed is: 
     
       1. A topical anesthetic gel composition comprising, (a) one or more topical anesthetic agents; and   (b) a pharmaceutical gel component, wherein said pharmaceutical gel component is Gelfoam®.   
     
     
       2. The composition of claim 1, wherein said Gelfoam® is contained in said composition in an amount of from about 6.0% to about 9.0% by weight, based upon the total weight of said composition. 
     
     
       3. A topical anesthetic gel composition, comprising: (a) tetracaine HCl, wherein said tetracaine HCl is contained in said composition in an amount of from about 0.01% to about 1.0% by weight, based upon the total weight of said composition;   (b) epinephrine HCl topical solution, wherein said epinephrine HCl is contained in said composition in an amount of from about 0.04% to about 0.1% by weight, based upon the total weight of said composition;   (c) cocaine HCl, wherein said cocaine HCl is contained in said composition in an amount of from about 3.0% to about 12.0% by weight, based upon the total weight of said composition; and   (d) GELFOAM®, wherein said GELFOAM® is contained in said composition in an amount of from about 6.0% to about 9.0% by weight, based upon the total weight of said composition.   
     
     
       4. A topical anesthetic gel composition, comprising: (a) lidocaine HCl, wherein said lidocaine HCl is contained in said composition in an amount of from about 0.9% to about 30% by weight, based upon the total weight of said composition;   (b) epinephrine HCl topical solution, wherein said epinephrine HCl is contained in said composition in an amount of from about 0.04% to about 0.1% by weight, based upon the total weight of said composition;   (c) tetracaine HCl, wherein said tetracaine HCl is contained in said composition in an amount of from about 0.01% to about 1.0% by weight, based upon the total weight of said composition; and   (d) GELFOAM®, wherein said GELFOAM® is contained in said composition in an amount of from about 6.0% to about 9.0% by weight, based upon the total weight of said composition.   
     
     
       5. A topical anesthetic gel composition, comprising: (a) lidocaine HCl, wherein said lidocaine HCl is contained in said composition in an amount of from about 0.9% to about 30% by weight, based upon the total weight of said composition; and   (b) GELFOAM®, wherein said GELFOAM® is contained in said composition in an amount of from about 6.0% to about 9.0% by weight, based upon the total weight of said composition.