Methods of treating androgenic alopecia with finasteride [17β-N-mono-substituted-carbamoyl-4-aza-5-α-androst-1-en-ones]

Abstract

17 beta -N-monosubstituted-carbamoyl-4-5 alpha -androst-1-en-3-ones of the formula <IMAGE> I wherein R1 is selected from hydrogen, methyl and ethyl and R2 is a branched chain alkyl of from 3-12 carbons, and R', R'', R''' are hydrogen or methyl are active as testosterone 5 alpha -reductase inhibitors and thus are useful topically for treatment of androgenic alopecia.

What is claimed is: 
     
       1. A method of treating androgenic alopecia which comprises orally administering to a human in need of such treatment a therapeutically effective amount of 17β-(N-tert-butylcarbamoyl)-4-aza-5α-androst-1-en-3-one. 
     
     
       2. The method of claim 1 wherein the androgenic alopecia is male pattern alopecia.