Ovulation control by regulating nitric oxide levels

Abstract

The stimulation of ovulation in a female may be achieved by administering a nitric oxide source, optionally in further combination with one or more of clomiphene, a gonadotropin, and an LH-RH agonist.

What is claimed is: 
     
       1. A method for inducing ovulation comprising administering L-arginine, sodium nitroprusside, nitroglycerin, isosorbide mononitrate or isosorbide dinitrate to a female in an amount stimulating ovulation. 
     
     
       2. A method for stimulating ovulation comprising: administering 10-100 mg of isosorbide mononitrate or isosorbide dinitrate to a female.   
     
     
       3. A method for stimulating ovulation comprising: administering an inducer of nitric oxide production selected from the group consisting of L-arginine, sodium nitroprusside, nitroglycerin, isosorbide mononitrate and isosorbide dinitrate; and administering a therapeutically effective amount of leuprolide acetate, wherein the therapeutically effective amount is about 1-10 mg/day.