US5747067AExpiredUtility

Co-processed products

86
Assignee: FMC CORPPriority: Dec 6, 1996Filed: Dec 6, 1996Granted: May 5, 1998
Est. expiryDec 6, 2016(expired)· nominal 20-yr term from priority
Inventors:Michael AuguelloThomas RuszkayGeorge E. Reier
A61K 9/2054A61K 9/2009
86
PatentIndex Score
86
Cited by
3
References
6
Claims

Abstract

Particulate pharmaceutical tablet excipient compositions comprising co-processed microcrystalline cellulose and particulate USP calcium carbonate having a particle size distribution of 7 to 22 mu m wherein the range of calcium carbonate to microcrystalline cellulose is 70:30 to 90:10.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
       1. Particulate pharmaceutical tablet excipient compositions comprising co-processed microcrystalline cellulose and particulate USP calcium carbonate, in which the calcium carbonate has an average particle size in the range of 7 to 22 μm and the weight ratio of calcium carbonate to microcrystalline cellulose is in the range of 70:30 to 90:10. 
     
     
       2. The composition of claim 1 wherein the calcium carbonate has a particle size of 10 to 18 μm. 
     
     
       3. The composition of claim 2 wherein the calcium carbonate has a particle size of 15±2 μm. 
     
     
       4. The composition of claim 1 wherein the range of calcium carbonate to microcrystalline cellulose is 80:20 to 85:15. 
     
     
       5. The composition of claim 4 wherein the calcium carbonate has a particle size of 12 to 18 μm. 
     
     
       6. The composition of claim 5 wherein the calcium carbonate has a particle size of 15±2 μm.

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