US5763242AExpiredUtility

Method for increasing transduction efficiency of recombinant retroviral vectors

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Assignee: UNIV JEFFERSONPriority: Feb 8, 1995Filed: Feb 8, 1995Granted: Jun 9, 1998
Est. expiryFeb 8, 2015(expired)· nominal 20-yr term from priority
Inventors:Hui ZhangRoger J. Pomerantz
C12N 15/63C12N 2740/13043C12N 15/86
53
PatentIndex Score
9
Cited by
66
References
1
Claims

Abstract

A method for improving the transduction efficiency of retroviral vectors into a host cell wherein the retroviral vectors are incubated with deoxyribonucleoside triphosphates prior to transduction into the host cell is provided.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
       1. A method for improving the transduction efficiency of a retroviral vector containing a heterologous gene into a host cell and increasing expression of the heterologous gene comprising incubating a retroviral vector with deoxyribonucleotide triphosphates prior to transduction into the host cell.

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