Pharmaceutical preparations containing polyunsaturated fatty acids, their esters or salts, together with antioxidant vitamins or provitamins

Abstract

Pharmaceutical preparations are described, useful in the prevention and/or treatment of atherosclerosis, of cardiovascular, nervous system, skin and malignant pathologies, containing 50 to 1000 mg of omega-3 fatty acids, their esters and their salts with inorganic and organic bases, as individual compounds or as a mixture, in combination with 10-40% by weight of antioxidant/reducing vitamins or provitamins.

I claim: 
     
       1. A pharmaceutical composition, comprising from 10-40% by weight Vitamin E, and a remainder by weight of a combination of (a) 4,7,10,13,16,19-cis docosahexaenoic acid (DHA),esters or salts thereof and (b) 5,8,11,14,17-cis eicosapentaenoic acid (EPA), pharmaceutically acceptable esters, or salts thereof. 
     
     
       2. A pharmaceutical composition according to claim 1, comprising between 20-30% vitamin E. 
     
     
       3. A pharmaceutical composition according to claim 1, comprising ethyl esters of DHA and EPA. 
     
     
       4. A pharmaceutical composition according to claim 1, comprising ethyl esters of DHA and EPA. 
     
     
       5. A pharmaceutical composition according to claim 1, comprising between 50 to 1,000 mg of DHA and EPA. 
     
     
       6. A pharmaceutical composition according to claim 2, comprising between 50 to 1,000 mg of DHA and EPA. 
     
     
       7. A pharmaceutical composition according to claim 3, comprising between 50 to 1,000 mg of DHA and EPA.