Cyanoacrylate compostions comprising an antimicrobial agent

Abstract

Disclosed are cyanoacrylate compositions comprising a compatible antimicrobial agent and, in particular, a compatible iodine containing antimicrobial agent. These compositions provide for in situ formation of an antimicrobial polymeric cyanoacrylate film on mammalian skin.

What is claimed is: 
     
       1. An antimicrobial cyanoacrylate composition which comprises: (a) a polymerizable cyanoacrylate ester which, in monomeric form, is represented by formula II: ##STR4## (b) an antimicrobially effective amount of polyvinylpyrrolidone iodine complex, wherein the viscosity of said composition is from about 2 to about 50,000 centipoise at 20° C.     
     
     
       2. The composition of claim 1 wherein the viscosity of the composition is from about 2 to about 1,500 centipoise at 20° C. 
     
     
       3. The composition of claim 1 wherein the viscosity of the composition is from about 5 to about 500 centipoise at 20° C. 
     
     
       4. The composition of claim 1 wherein the viscosity of the composition is from about 1,500 to about 50,000 centipoise at 20° C.