Percutaneous administration tape preparation

Abstract

There provided a percutaneous administration tape preparation which can attach well to the skin surface even in the case of the permeation of water after attaching and can be easily detached from the skin surface without giving the skin simulation such as peeling off and the injury of the horny layer. The percutaneous administration tape preparation comprises a sheet-form support, a drug-containing pressure-sensitive adhesive layer, and a separator, wherein the drug-containing pressure-sensitive adhesive layer comprises a uniform dispersed state containing from 50 to 95% by weight one or more kinds of elastomers, from 5 to 50% by weight a hygroscopic material, and a percutaneous absorption drug so that a part of the hygroscopic material contained therein remains on the applied surface at detaching the tape preparation from the applied surface.

What is claimed is: 
     
       1. A percutaneous administration tape preparation composed of a sheet-form support, a drug-containing pressure-sensitive adhesive layer, and a separator, wherein the drug-containing pressure-sensitive adhesive layer comprises a uniform dispersed state containing from 50 to 95% by weight one or more kinds of elastomers, from 5 to 50% by weight a hygroscopic material, and a percutaneous absorption drug so that a part of the hygroscopic material contained therein remains on the applied surface at detaching the tape preparation from the applied surface, and wherein said hygroscopic material absorbs from 3 to 30 wt. % water based on a water-free weight of said pressure-sensitive adhesive layer. 
     
     
       2. A percutaneous administration tape preparation of claim 1, wherein the elastomer is selected from polyisobutylene, an acrylic polymer, and a styrene/isoprene/styrene block copolymer. 
     
     
       3. A percutaneous administration tape preparation of claim 1, wherein the hygroscopic material is at least one selected from carboxymethyl cellulose sodium, dextrin, pectin, and gelatin.