US5872237AExpiredUtilityPatentIndex 87

Megabase transcript map: novel sequences and antibodies thereto

Assignee: MERCATOR GENETICS INCPriority: Apr 4, 1996Filed: Oct 1, 1996Granted: Feb 16, 1999

Est. expiryApr 4, 2016(expired)· nominal 20-yr term from priority

Inventors:FEDER JOHN NATHAN KRONMAL GREGORY SCOTT LAUER PETER M RUDDY DAVID A THOMAS WINSTON TSUCHIHASHI ZENTA WOLFF ROGER K

C07K 14/47C12Q 1/6883C07K 14/70503C12Q 2600/158C07K 14/70539A61K 38/00

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Abstract

A fine structure map of the 1 megabase region surrounding the candidate HH gene is provided, along with 250 KB of DNA sequence and 8 loci corresponding to candidate genes within the 1 megabase region. These loci are useful as genetic markers for further mapping studies. Additionally, the eight cDNA sequences corresponding to those loci are useful, for example, for the isolation of other genes in putative gene families, and as probes for diagnostic assays. Additionally, the proteins encoded by those cDNAs are useful in the generation of antibodies for analysis of gene expression and in diagnostic assays, and in the purification of related proteins.

Claims

exact text as granted — not AI-modified

What is claimed is: 
     
       1. An isolated nucleic acid sequence of approximately 250 kb comprising the sequence of SEQ ID NO:20.

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