US5945438AExpiredUtility

Triazole derivative and pharmaceutical comprising the same as an effective ingredient

66
Assignee: SS PHARMACEUTICAL COPriority: Dec 22, 1995Filed: Dec 17, 1996Granted: Aug 31, 1999
Est. expiryDec 22, 2015(expired)· nominal 20-yr term from priority
C07D 249/08C07D 231/12C07D 303/34C07D 233/56C07D 249/10A61K 31/41
66
PatentIndex Score
9
Cited by
13
References
11
Claims

Abstract

Described is a triazole derivative represented by the formula (1) or salt thereof, preparation process thereof, preparation intermediates represented by the formulas (2) and (3), and a pharmaceutical comprising the compound represented by the formula (1) or salt thereof. wherein n stands for 0, 1 or 2, X1 represents H or F and Y1 and Y2 each independently represents H, halogen or CF3.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
       1. A triazole derivative represented by the following formula (1): ##STR4## wherein Y 1  and Y are the same or different and each independently represents a hydrogen atom, a halogen atom or a trifluoromethyl group, and n stands for 0, 1 or 2; or a pharmacologically acceptable salt thereof. 
     
     
       2. A pharmaceutical composition comprising a pharmacologically effective amount of a triazole derivative or a pharmacologically acceptable salt thereof as claimed in claim 1 and a pharmacologically acceptable carrier. 
     
     
       3. A composition according to claim 2 which is a mycocide composition. 
     
     
       4. A method for treating mycosis, which comprises administering to a patient an effective amount of a triazole derivative or a pharmacologically acceptable salt thereof as claimed in claim 1. 
     
     
       5. A method according to claim 4, wherein the triazole derivative or pharmacologically acceptable salt thereof is administered in a pharmacologically acceptable carrier. 
     
     
       6. A triazole derivative according to claim 1, wherein Y 1  and Y 2  are halogen. 
     
     
       7. A triazole derivative according to claim 6, wherein Y 1  and Y 2  are fluorine. 
     
     
       8. A pharmaceutical composition comprising a pharmacologically effective amount of a triazole derivative or a pharmacologically acceptable salt thereof as claimed in claim 6, and a pharmacologically acceptable carrier. 
     
     
       9. A pharmaceutical composition comprising a pharmacologically effective amount of a triazole derivative or a pharmacologically acceptable salt thereof as claimed in claim 7, and a pharmacologically acceptable carrier. 
     
     
       10. A method for treating mycosis, which comprises administering to a patient an effective amount of a composition comprising a triazole derivative or a pharmacologically acceptable salt thereof as claimed in claim 8. 
     
     
       11. A method for treating mycosis, which comprises administering to a patient an effective amount of a composition comprising a triazole derivative or a pharmacologically acceptable salt thereof as claimed in claim 9.

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