US5945438AExpiredUtility
Triazole derivative and pharmaceutical comprising the same as an effective ingredient
Est. expiryDec 22, 2015(expired)· nominal 20-yr term from priority
Inventors:Minoru TokizawaSunao TakedaYasushi KanekoHiromichi EtoKazuya IshidaKazunori MaebashiMasaru MatsumotoTakemitsu AsaokaSusumu SatoHideaki Matsuda
C07D 249/08C07D 231/12C07D 303/34C07D 233/56C07D 249/10A61K 31/41
66
PatentIndex Score
9
Cited by
13
References
11
Claims
Abstract
Described is a triazole derivative represented by the formula (1) or salt thereof, preparation process thereof, preparation intermediates represented by the formulas (2) and (3), and a pharmaceutical comprising the compound represented by the formula (1) or salt thereof. wherein n stands for 0, 1 or 2, X1 represents H or F and Y1 and Y2 each independently represents H, halogen or CF3.
Claims
exact text as granted — not AI-modifiedWhat is claimed is:
1. A triazole derivative represented by the following formula (1): ##STR4## wherein Y 1 and Y are the same or different and each independently represents a hydrogen atom, a halogen atom or a trifluoromethyl group, and n stands for 0, 1 or 2; or a pharmacologically acceptable salt thereof.
2. A pharmaceutical composition comprising a pharmacologically effective amount of a triazole derivative or a pharmacologically acceptable salt thereof as claimed in claim 1 and a pharmacologically acceptable carrier.
3. A composition according to claim 2 which is a mycocide composition.
4. A method for treating mycosis, which comprises administering to a patient an effective amount of a triazole derivative or a pharmacologically acceptable salt thereof as claimed in claim 1.
5. A method according to claim 4, wherein the triazole derivative or pharmacologically acceptable salt thereof is administered in a pharmacologically acceptable carrier.
6. A triazole derivative according to claim 1, wherein Y 1 and Y 2 are halogen.
7. A triazole derivative according to claim 6, wherein Y 1 and Y 2 are fluorine.
8. A pharmaceutical composition comprising a pharmacologically effective amount of a triazole derivative or a pharmacologically acceptable salt thereof as claimed in claim 6, and a pharmacologically acceptable carrier.
9. A pharmaceutical composition comprising a pharmacologically effective amount of a triazole derivative or a pharmacologically acceptable salt thereof as claimed in claim 7, and a pharmacologically acceptable carrier.
10. A method for treating mycosis, which comprises administering to a patient an effective amount of a composition comprising a triazole derivative or a pharmacologically acceptable salt thereof as claimed in claim 8.
11. A method for treating mycosis, which comprises administering to a patient an effective amount of a composition comprising a triazole derivative or a pharmacologically acceptable salt thereof as claimed in claim 9.Cited by (0)
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