Water-soluble vitamin composition having excellent tablet properties and process for production thereof

Abstract

There is disclosed a water-soluble vitamin composition which containing about 90 to 99.8% by weight of a water-soluble vitamin, a polymer binder and at least one additive selected from the group consisting of monosaccharides, disaccharides, sugar alcohols, dextrin and organic acids, which can provide a tablet having high mechanical strength (hardness) with less compression problem and easy disintegration, upon compression. A process for producing the composition is also disclosed.

What is claimed is: 
     
       1. An L-ascorbic acid composition which comprises about 90 to 99.8% by weight of L-ascorbic acid, hydroxypronylmethyl cellulose and at least one additive selected from the group consisting of maltitol, lactitol, glucose, L-alanine, fructose, mannose, galactose, potassium gluconate, sucrose, gluconic acid, sodium gluconate, nicotinamide, Palatinit®, sodium glucuronate, lactose and dextrin, obtained by carrying out granulation by a fluidized bed granulation method, while coating L-ascorbic acid with a solution of the polymer and the additive. 
     
     
       2. A process for producing a L-ascorbic acid composition comprising about 90 to 99.8% by weight of L-ascorbic acid, hydroxypropylmethyl cellulose and at least one additive selected from the group consisting of maltitol, lactitol, glucose, L-alanine, fructose, mannose, galactose, potassium gluconate, sucrose, gluconic acid, sodium gluconate, nicotinamide, Palatinit®, sodium glucuronate, lactose and dextrin, said process comprising carrying out granulation by a fluidized bed granulation method, while coating L-ascorbic acid with a solution of the polymer and the additive. 
     
     
       3. An L-ascorbic acid tablet obtained from the composition according to claim 1. 
     
     
       4. A composition according to claim 1, wherein the additive is dextrin.