Method for producing a plastic vessel containing an albumin preparation

Abstract

To provide a plastic vessel containing an albumin preparation which completely restrains formation of thermally denatured albumin, a plastic molded member in a cylindrical shape is extruded in a molten state into opened dies, one end of which is closed in the dies, and a vessel is molded by blowing a compressed gas into the molded member in the dies or by bringing inner portions of the dies into a vacuum state. While the vessel is still disposed in the dies, an albumin preparation is introduced from an opening portion into an inner portion of the vessel and, therefore, the albumin preparation can be filled into the vessel in a sterilized state without being brought into contact with the atmosphere. Then, an opening portion of the vessel filled with the albumin preparation is hermetically sealed at an internal temperature of the opening portion of about 40° to 70° C. Thus formation of thermally denatured albumin can be completely restrained. A METHOD FOR PRODUCING A PLASTIC VESSEL CONTAINING AN ALBUMIN PREPARATION

What is claimed is:  
     
       1. A method for producing a plastic vessel containing a serum albumin preparation comprising 
       (1) melting a plastic material and forming a parison which is a plastic member in a cylindrical shape having one closed end,  
       (2) arranging the parison in an inner portion of a pair of the body dies,  
       (3) blowing a compressed gas into an inner portion of the parison or applying a vacuum to the inner portion of the pair of body dies to form a main body of a plastic vessel,  
       (4) while the vessel is arranged in said dies, introducing a serum albumin preparation through an opening portion of the plastic vessel into an inner portion of the plastic vessel, and  
       (5) hermetically sealing the opening portion of the plastic vessel by pressing with a pair of head dies at an internal temperature of about 40° to 70° C of the opening portion of the vessel containing the albumin preparation to form a head portion.