US6346395B1ExpiredUtility

Nucleic acids encoding Streptococcus pneumoniae FabG

46
Assignee: SMITHKLINE BEECHAM CORPPriority: Jan 27, 1999Filed: Jan 27, 1999Granted: Feb 12, 2002
Est. expiryJan 27, 2019(expired)· nominal 20-yr term from priority
Inventors:Alison Francis ChalkerChristine DebouckDavid John HolmesKaren Anne IngrahamDeborah Dee JaworskiAnna KosmatkaDamien McdevittJeffrey MooneyStewart Campbell PearsonChi SoNicola Gail WallisMin WangRichard Lloyd WarrenYi Yi Zhong
C12Y 101/011A61K 38/00C12N 9/0006
46
PatentIndex Score
6
Cited by
5
References
14
Claims

Abstract

The invention provides FabG polypeptides and polynucleotides encoding FabG polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing FabG polypeptides to screen for antibacterial compounds.

Claims

exact text as granted — not AI-modified
What is claimed is:  
     
       1. An isolated polynucleotide segment comprising a nucleic acid sequence, wherein the nucleic acid sequence encodes a polypeptide comprising SEQ ID NO:2. 
     
     
       2. A vector comprising the isolated polynucleotide of  claim 1 . 
     
     
       3. An isolated host cell comprising the vector of  claim 2 . 
     
     
       4. A process for producing a polypeptide comprising culturing the host cell of  claim 3  under conditions sufficient for production of the polypeptide, which polypeptide comprises SEQ ID NO:2. 
     
     
       5. An isolated polynucleotide segment comprising a nucleic acid sequence, wherein the nucleic acid sequence encodes a polypeptide consisting of SEQ ID NO:2. 
     
     
       6. A vector comprising the isolated polynucleotide of  claim 5 . 
     
     
       7. An isolated host cell comprising the vector of  claim 6 . 
     
     
       8. A process for producing a polypeptide comprising culturing the host cell of  claim 7  under conditions sufficient for production of the polypeptide, which polypeptide consists of SEQ ID NO:2. 
     
     
       9. An isolated polynucleotide segment comprising the full complement of the entire length of the nucleic acid sequence of  claim 1 . 
     
     
       10. A vector comprising the isolated polynucleotide of  claim 9 . 
     
     
       11. An isolated host cell comprising the vector of  claim 10 . 
     
     
       12. An isolated polynucleotide segment comprising the full complement of the entire length of the nucleic acid sequence of  claim 5 . 
     
     
       13. A vector comprising the isolated polynucleotide of  claim 12 . 
     
     
       14. An isolated host cell comprising the vector of  claim 13 .

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