Thin porous layers for thin-layer chromatography

Abstract

Novel separation materials for thin layer chromatography are disclosed; these consist of a support and a separation medium layer and are obtainable by the following process steps: a) cleaning of the support; b) application of a liquid film comprising a polysilicic ester to a support; c) introduction of the support with the liquid film into an atmosphere which effects hydrolysis and further polymerization of the polysilicic ester; d) hydrolysis and further polymerization of the polysilicic ester at constant temperature; e) washing of the silica layer; f) drying of the silica layer. The silica gel surface of the separation material of the invention can be modified by means of separation effectors.

What is claimed is:  
     
       1. Separation material for thin layer chromatography consisting of a support and a separation medium layer obtainable by the following process steps: 
       a) cleaning of the support;  
       b) application of a liquid film comprising a polysilicic ester to a support;  
       c) introduction of the support with the liquid film into an atmosphere which effects hydrolysis and further polymerization of the polysilicic ester;  
       d) hydrolysis and further polymerization of the polysilicic ester at constant temperature;  
       e) washing of the silica layer;  
       f) drying of the silica layer.  
     
     
       2. Separation material according to  claim 1 , further characterized by modification of the silica gel surface by means of separation effectors. 
     
     
       3. Process for producing a separation material for thin layer chromatography, which comprises the following steps: 
       a) cleaning of the support;  
       b) application of a liquid film comprising a polysilicic ester to a support;  
       c) introduction of the support with the liquid film into an atmosphere which effects hydrolysis and further polymerization of the polysilicic ester;  
       d) hydrolysis and further polymerization of the polysilicic ester at constant temperature;  
       e) washing of the silica layer;  
       f) drying of the silica layer.  
     
     
       4. Process according to  claim 3 , wherein the said liquid film is applied by spraying on. 
     
     
       5. Process according to  claim 3 , wherein the said liquid film is applied by firstly applying the liquid at one point and subsequently rotating the support about the point of application, with the axis of rotation being perpendicular to the plane of the support. 
     
     
       6. Process according to  claim 3 , wherein the said liquid film is applied by means of a roller. 
     
     
       7. A method of separating at least two substances by thin layer chromatography comprising applying the at least two materials to the separation materials of  claim 1  and eluting the at least two substances.