Dry skin remedies

Abstract

Novel dry skin remedies useful for treatment dry skin, containing as the active ingredient spiro [oxathiolane-quinuclidine] derivatives represented by general formula (I) or acid addition salts thereof, desirably cis-2-methylspiro [1,3-oxathiolane-5,3′-quinuclidine] hydrochloride. The remedies promote the secretion of sebaceous and sweat glands through oral or parenteral administration to treat dry skin, thus being useful as drugs.

What is claimed is:  
     
       1. A therapeutic agent for the treatment of dry skin, comprising a compound represented by the following formula (I) or an acid addition salt thereof as an active ingredient;                    
       wherein, R 1  and R 2  may be the same or different, and each represents hydrogen, alkyl, cyclopentyl, cyclohexyl, aryl, or diarylmethilol groups or an alkyl group which is substituted by one or more aryl groups. 
     
     
       2. A therapeutic agent for the treatment of dry skin according to  claim 1 , wherein the acid addition salt is 2-methylspiro (1,3-oxathiolane-5,3′)quinuclidine hydrochloride. 
     
     
       3. A therapeutic agent for the treatment of dry skin according to  claim 2 , in which the 2-methylspiro (1,3-oxathiolane-5,3′)quinuclidine hydrochloride is a cis-isomer.