Treating eczema with a combination of isotonic saline ocean® and nasal mast cell stabilizers

Abstract

The present invention relates to the prevention and treatment of atopic dermatitis and treatment of atopic dermatitis and other eczematous disorders by application of topical mast cell stabilizers including cromolyn sodium, nedocromil or lodoxamide, in a vehicle of a buffered isotonic saline solution (OCEAN®).

What is claimed is:  
     
       1. A topical preparation suitable for application as spray or drops, said preparation comprising an effective amount of a topical mast cell stabilizer to inhibit release of mast cell mediators, and said topical mast cell stabilizer selected from the group consisting of cromolyn sodium, nedocromil and lodoxamide, and an isotonic solution containing 0.65% sodium chloride in water with phenylcarbinol and benzalkonium chloride. 
     
     
       2. The preparation of  claim 1 , wherein the effective amount of cromolyn sodium in the range of a concentration of 0.5% to 5.0%. 
     
     
       3. The preparation of  claim 1 , wherein the effective amount of nedocromil is in the range of a concentration of 0.1% to 8.0%. 
     
     
       4. The preparation of  claim 1 , wherein the effective amount of lodoxamide is in the range of a concentration of 0.1% to 10%.