Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for preparing the same

Abstract

Optically active 1-substituted phenyl-2-nitro alcohol derivatives having the formula (1)and the process for producing thereof, and 1-substituted phenyl-2-amino alcohol derivatives having the formula (2)and the process for producing thereof from the optically active 1-substituted phenyl-2-nitro alcohol derivatives. From these nitro alcohols, pharmaceuticals such as (R)-albutamin and (R)-sarmeterol useful as a bronchodilator is obtained via optically active amino alcohols which are useful pharmaceutical intermediates.</PTEXT>

What is claimed is:  
     
       1. An optically active alcohol of the following formula (1-1)                    
       in which R 5  and R 6  both represent a t-butyldimethylsilyl group, respectively; R 4  represents a hydrogen atom; and * represents an optically active site.