US6858733B2ExpiredUtilityPatentIndex 73

Compounds for generating chemiluminescence with a peroxidase

Assignee: LUMIGEN INCPriority: Dec 20, 2001Filed: Jul 25, 2002Granted: Feb 22, 2005

Est. expiryDec 20, 2021(expired)· nominal 20-yr term from priority

Inventors:AKHAVAN-TAFTI HASHEM DE SILVA RENUKA XIE WENHUA

C07F 9/65586C07D 411/06G01N 2333/908C07D 409/06C07F 9/64C12Q 1/28Y10S435/968C07D 219/02G01N 33/581

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Abstract

Novel compounds comprising a C—C double bond substituted at one carbon with two sulfur atom-containing groups are disclosed. The compounds are useful in methods and compositions for generating chemiluminescence rapidly by reaction with a peroxidase enzyme and a peroxide. The chemiluminescence thus produced can be used as a detectable signal in assays for peroxidase enzymes or peroxide-producing enzymes and in assays employing enzyme-labeled specific binding pairs.

Claims

exact text as granted — not AI-modified

1. A compound selected from the group: 
                 
 
     
     
       2. The compound of  claim 1  which has the formula:

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