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US6911208B2ExpiredUtilityPatentIndex 48

Antigenic protein originating in malassezia

Assignee: TAKARA BIO INCPriority: Dec 12, 1995Filed: Apr 1, 2002Granted: Jun 28, 2005
Est. expiryDec 12, 2015(expired)· nominal 20-yr term from priority
Inventors:TAKESAKO KAZUTOHOKADO TAKASHIYAGIHARA TOMOKOKURODA MASANOBUONISHI YOSHIMIKATO IKUNOSHINAKIYAMA KAZUOYASUEDA HIROSHIYAMAGUCHI HIDEYO
A61K 39/00C12Q 1/68C07K 14/37Y10S530/858C12P 21/00A61K 39/0002C07K 16/14A61K 38/00C12N 15/11
48
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Claims

Abstract

A substantially pure, isolated, antigenic protein from fungi of the genus Malassezia , characterized in that said antigenic protein has a binding ability to IgE antibodies from patients with allergies; an antigenic fragment derived from the antigenic protein; and an antibody against the antigenic protein or fragments thereof. According to the present invention, there can be provided an isolated and purified antigenic protein having high purity from Malassezia , antigenic fragments thereof, and a specific antibody against those antigenic protein or fragments thereof. In addition, there can be provided a diagnostic agent, a therapeutic agent, or a prophylactic drug for Malassezia allergies, wherein the agent includes, as an active ingredient, the antigenic protein or fragments thereof.

Claims

exact text as granted — not AI-modified
1. An isolated and purified antigenic protein comprising the amino acid sequence of SEQ ID NO:10. 
     
     
       2. The antigenic protein of  claim 1 , wherein said protein has a binding affinity to IgE antibodies from patients with  Malassezia allergies.

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