Use of botuline toxin to obtain a product to be used in articular pathologies, particularly coxarthrosis, epicondylitis and rotator muscle cap pathology

Abstract

Use of botulin toxin to obtain a product intended to be administered intramuscular with lissive effect in treating articular pathologies, particularly coxarthrosis, or arthrosis of the hip, epicondylitis of the elbow and rotator muscle cap pathology of the shoulder.

1. A method for treating the symptom of endo-articular pressure in a patient suffering from coxarthrosis, comprising administering a botulinum toxin type A composition into a thigh muscle of said patient, wherein said thigh muscle is selected from at least one member of the group consisting of the long adductor muscle, great adductor muscle, iliopsoas and tensor muscle of the fascia lata, wherein said composition comprises a mixture of botulinum toxin type A and a physiological solution containing between 0.45% and 1.0% sodium chloride, and wherein said endo-articular pressure exerted by said thigh muscle on the femoral head against the cotyl in the hip is reduced. 
     
     
       2. The method according to  claim 1 , wherein said intra-muscular administering of the composition is guided with an electromyographic guide. 
     
     
       3. The method according to  claim 1 , wherein the botulinum toxin type A is administered at a dose between 25 and 100 MU. 
     
     
       4. The method according to  claim 1 , wherein the botulinum toxin type A is administered at a dose of about 50 MU. 
     
     
       5. The method according to  claim 1 , said physiological solution contains about 0.9% sodium chloride. 
     
     
       6. The method according to  claim 1 , wherein said composition further comprises at least one aggregate selected from the group consisting of human albumin, sodium-based compounds, lactose and hydrochloric acid.