US7511120B2ExpiredUtilityA1
Glycosylated G-CSF obtained from a transgenic chicken
Est. expiryOct 16, 2017(expired)· nominal 20-yr term from priority
C07K 14/505C12N 2830/15C07K 2319/30A01K 2267/01C12N 2830/008A61P 7/00A01K 67/0275A01K 2217/05C07K 14/535C12N 2799/027C07K 14/70521A61K 38/00A01K 2227/30C12N 15/8509
84
PatentIndex Score
5
Cited by
102
References
10
Claims
Abstract
Granulocyte colony stimulating factor obtained from eggs laid by transgenic avians having newly described G-CSF glycosylation patterns.
Claims
exact text as granted — not AI-modified1. A composition comprising an isolated human G-CSF having a chicken-derived glycosylation pattern wherein the glycosylation pattern is other than that of G-CSF produced in a CHO cell.
2. An isolated human G-CSF having a chicken-derived glycosylation pattern wherein the glycosylation pattern is other than that of G-CSF produced in a CHO cell.
3. The composition of claim 1 wherein the G-CSF is present in a hard shell egg.
4. The composition of claim 1 wherein an G-CSF is glycosylated in an oviduct cell of an avian.
5. The composition of claim 4 wherein the oviduct cell is a tubular gland cell.
6. The composition of claim 1 wherein an G-CSF is glycosylated in an oviduct cell of a chicken.
7. The composition of claim 1 wherein the G-CSF is glycosylated at threonine 133.
8. The composition of claim 1 wherein the composition is a pharmaceutical composition.
9. The composition of claim 1 wherein the G-CSF has the amino acid sequence of SEQ ID NO: 41.
10. The composition of claim 1 wherein the glycosylation pattern is other than that of G-CSF produced in a human cell.Cited by (0)
No later patents cite this yet.
References (0)
No backward citations on record.