US7989498B2ExpiredUtilityPatentIndex 90
Inhibitors of IMPDH enzyme
Est. expiryApr 26, 2019(expired)· nominal 20-yr term from priority
Inventors:SAUNDERS JEFFREY OELBAUM DANIELNOVAK PERRY MNAEGELE DOUGLASBETHIEL RANDY SRONKIN STEVEN MBADIA MICHAEL CFRANK CATHARINESTAMOS DEAN PWALTERS WILLIAMPEARLMAN DAVID
C07C 323/42C07C 311/29C07C 317/40C07C 311/21C07D 213/75C07C 217/84C07D 271/06C07D 263/32C07D 413/12C07C 235/64A61K 31/4965C07D 317/68C07D 307/91C07C 333/08A61K 31/53
90
PatentIndex Score
19
Cited by
69
References
1
Claims
Abstract
The present invention relates to compounds which inhibit IMPDH. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting IMPDH enzyme activity and consequently, may be advantageously used as therapeutic agents for IMPDH mediated processes. This invention also relates to methods for inhibiting the activity of IMPDH using the compounds of this invention and related compounds.
Claims
exact text as granted — not AI-modified1. A composition comprising:
a) a compound selected from the group consisting of:
and
b) a carrier, adjuvant, or vehicle, which is pharmaceutically acceptable for oral administration or administration by injection.Cited by (0)
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