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US7998693B2ExpiredUtilityPatentIndex 49

Gene specific to cancer and diagnosis kit using the same

Assignee: UNIV CHIBA NAT UNIV CORPPriority: Jan 5, 2005Filed: Jan 5, 2006Granted: Aug 16, 2011
Est. expiryJan 5, 2025(expired)· nominal 20-yr term from priority
Inventors:SHIMADA HIDEAKITOMONAGA TAKESHIMATSUSHITA KAZUYUKIOCHIAI TAKENORINOMURA FUMIO
G01N 33/57595C12Q 1/6886C12Q 2600/158C07K 14/47
49
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1
Claims

Abstract

The present invention provides a new additional identification of a gene related to cancer expression and a diagnostic kit using the same.

Claims

exact text as granted — not AI-modified
1. A method for detecting rectal cancer or colon cancer, comprising the steps of: measuring an expression level of a protein consisting of an amino-acid sequence as in SEQ ID NO: 2 for each of two collected cells, wherein one of said two collected cells is a cell from a non-cancer tissue and the other of said two collected cells is a cell from a tissue suspected to be a cancer tissue, and wherein said measuring is performed comprising using western blot analysis and using an antibody against the protein consisting of the amino-acid sequence as in SEQ ID NO: 2;
 calculating a ratio between the measured expression levels; and 
 determining the other cell is a rectal cancer or colon cancer cell if the ratio between the measured expression levels is equal to or greater than 1.7.

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