Capsule for taking an active substance which can be inhaled

Abstract

The invention relates to a novel capsule for receiving an active substance to be administered by inhalation, which is preferably intended for use in a powder inhaler operating on the Bernoulli principle.

1. A capsule for holding a pharmaceutical composition in a Bernoulli inhaler, the capsule comprising:
 two parts in communication with one another such that, in a closed state, the two parts define the longitudinal axis and a transverse axis which is shorter in relation to the longitudinal axis; and 
 elevations on an outer surface wherein the elevations are in a form of at least one of longitudinal ribs, and helical ribs, 
 wherein features forming an outer contour of the closed capsule are symmetrical with respect to a transverse plane which bisects the longitudinal axis, the following features being excluded from conditions of symmetry: fine structures of any seams comprising sealed seams of individual parts of the capsule, elements formed on a capsule surface which are smaller than 0.1 mm, and/or angles of taper up to 5°. 
 
     
     
       2. The capsule of  claim 1 , wherein the two parts are operable to be pushed telescopically one inside the other along the longitudinal axis. 
     
     
       3. The capsule of  claim 2 , wherein a seam created between the two parts of the closed capsule is offset from the center by 0 to 12% of the outer longitudinal length. 
     
     
       4. The capsule of  claim 1 , wherein any seam created between the two parts when the capsule is closed is offset from the center by 0 to 12% of the outer longitudinal length. 
     
     
       5. The capsule of  claim 1 , wherein the capsule has a cylindrical outer contour. 
     
     
       6. The capsule of  claim 5 , wherein the capsule has tapering sealed ends. 
     
     
       7. The capsule of  claim 1 , wherein the capsule comprises a member of the D ∞h  symmetry group in terms of its outer contour, irrespective of the seam between the two parts of the capsule and irrespective of any manufacturing tolerances. 
     
     
       8. The capsule of  claim 1 , wherein features located on the outer contour of the capsule surface and forming a symmetrical pair may have a tolerance and inaccuracy deviating from the symmetry of 0.15 mm in each case. 
     
     
       9. The capsule of  claim 1 , wherein the elevations are in the form of at least one of ribs with sharp edges, ribs with soft undulating transitions, ribs in the form of pins and combinations thereof.