Human GIL-19/AE289 proteins

Abstract

Novel human GIL-19/AE289 protein is disclosed which shows a high degree of homology to interleukin-10 (IL-10). Polynucleotides encoding such protein are also enclosed.

1. An isolated protein comprising an amino acid sequence selected from the group consisting of:
 (a) the amino acid sequence of SEQ ID NO:2; 
 (b) a fragment of the amino acid sequence of SEQ ID NO:2, the fragment comprising thirty contiguous amino acids of SEQ ID NO:2; and 
 (c) the amino acid sequence encoded by the cDNA insert of clone hGIL-19/AE289 deposited under accession number ATCC 207231; 
 
       the protein being substantially free from other mammalian proteins.