Herbal mixture extract of Rehmanniae radix preparata and Acanthopanacis cortex and a composition comprising the same for prevention and treatment of osteoporosis

Abstract

The present invention relates to a herbal mixture extract of Rehmanniae Radix Preparata and Acanthopanacis Cortex and a composition comprising the same for the prevention and treatment of osteoporosis. The herbal mixture extract of the present invention enhances the expression of osteoprotegerin (OPG) in osteoblasts and effectively inhibits the generation and activation of osteoclasts, so that it can be effectively used for the prevention and treatment of osteoporosis.

1. An herbal extract mixture consisting of an extract of  Rehmanniae Radix  Preparata and an extract of  Acanthopanacis Cortex , wherein the extract of  Rehmanniae Radix  Preparata and the extract of  Acanthopanacis Cortex  are mixed at a weight ratio of 16:1 to 1:4. 
     
     
       2. The herbal mixture extract as set forth in  claim 1 , in which  Rehmanniae Radix  Preparata extract and  Acanthopanacis Cortex  extract are mixed at a weight ratio of 8:1 to 1:4. 
     
     
       3. The herbal mixture extract as set forth in  claim 1 , in which  Rehmanniae Radix  Preparata extract and  Acanthopanacis Cortex  extract are mixed at a weight ratio of 4:1 to 1:1.