Stabilized subtilisin composition

Abstract

The present invention relates to a liquid detergent composition comprising a surfactant, a subtilisin and a protease stabilizer that is 3-chlorobenzoic acid, 4-chlorobenzoic acid, 3-chlorophenylacetic acid, 3,5-dichlorobenzoic acid, 3-(3-chlorophenyl)propionic acid or their corresponding salts. The composition can further comprise a another enzyme that is a lipase, an amylase, a cellulase or mixtures thereof. The stabilizer can be present at a concentration of 0.001 to 20% w/w. The concentration of the subtilisin can be at least 1.5 g/L.

1. A liquid detergent composition comprising a surfactant, a subtilisin and a protease stabilizer, wherein the protease stabilizer is selected from the group consisting of 3-chlorobenzoic acid, 4-chlorobenzoic acid, 3-chlorophenylacetic acid, 3,5-dichlorobenzoic acid, 3-(3-chlorophenyl)propionic acid, and their corresponding salts. 
     
     
       2. The liquid detergent composition in accordance with  claim 1 , further comprising a second enzyme comprising amylase, lipase, cellulase, oxidoreductase, and mixtures thereof. 
     
     
       3. The liquid detergent composition according to  claim 1 , wherein said protease stabilizer is 0.001-20% w/w of the liquid detergent composition. 
     
     
       4. The liquid detergent composition in accordance with  claim 1 , comprising a second enzyme, wherein the second enzyme is an amylase. 
     
     
       5. The liquid detergent composition in accordance with  claim 1 , wherein the subtilisin is present in the liquid detergent composition in an amount of at least 1.5 g/L. 
     
     
       6. The liquid detergent composition in accordance with  claim 1 , wherein the composition has a pH of at least 8. 
     
     
       7. The liquid detergent composition of  claim 1 , wherein the protease stabilizer is 3-chlorobenzoic acid or a salt thereof. 
     
     
       8. The liquid detergent composition of  claim 1 , wherein the protease stabilizer is 4-chlorobenzoic acid or a salt thereof. 
     
     
       9. The liquid detergent composition of  claim 1 , wherein the protease stabilizer is 3-chlorophenylacetic acid or a salt thereof. 
     
     
       10. The liquid detergent composition of  claim 1 , wherein the protease stabilizer is 3,5-dichlorobenzoic acid or a salt thereof. 
     
     
       11. The liquid detergent composition of  claim 1 , wherein the protease stabilizer is 3-(3-chlorophenyl)propionic acid or a salt thereof. 
     
     
       12. The liquid detergent composition of  claim 1  further comprising an amylase. 
     
     
       13. The liquid detergent composition of  claim 1  further comprising a lipase. 
     
     
       14. The liquid detergent composition of  claim 1  further comprising a cellulase. 
     
     
       15. The liquid detergent composition of  claim 1  further comprising an oxidoreductase. 
     
     
       16. A liquid detergent composition comprising a surfactant, a subtilisin and a protease stabilizer, wherein the protease stabilizer is 3-chlorobenzoic acid or a salt thereof, and wherein said stabilizer is 0.001-20% w/w of the liquid composition. 
     
     
       17. The liquid detergent composition in accordance with  claim 16 , further comprising a second enzyme comprising amylase, lipase, cellulase, oxidoreductase, and mixtures thereof. 
     
     
       18. A liquid detergent composition comprising a surfactant, a subtilisin and a protease stabilizer, wherein the protease stabilizer is selected from the group consisting of 3-chlorobenzoic acid, 4-chlorobenzoic acid, 3-chlorophenylacetic acid, 3,5-dichlorobenzoic acid, 3-(3-chlorophenyl)propionic acid, and their corresponding salts, wherein the composition has a pH of at least 8, and wherein said stabilizer is 0.001-20% w/w of the liquid composition. 
     
     
       19. The liquid detergent composition of  claim 18 , wherein the protease stabilizer is 3-chlorobenzoic acid or a salt thereof. 
     
     
       20. The liquid detergent composition in accordance with  claim 18 , further comprising a second enzyme comprising amylase, lipase, cellulase, oxidoreductase, and mixtures thereof.