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US8153676B2ExpiredUtilityPatentIndex 30

Use of compounds of formula A-R-Xo pharmaceutically acceptable salts thereof for producing a pharmaceutically preparations

Assignee: MUELLER-ENOCH DIETERPriority: Apr 28, 2006Filed: Apr 27, 2007Granted: Apr 10, 2012
Est. expiryApr 28, 2026(expired)· nominal 20-yr term from priority
Inventors:MUELLER-ENOCH DIETERHAEHNER THOMAS
A61P 9/00A61P 43/00A61P 39/02A61P 3/10A61P 35/00A61P 31/14A61P 25/32A61K 31/164A61K 31/19A61P 1/18A61K 31/6615A61K 31/133A61P 1/16A61K 31/685A61K 31/4172A61K 31/4164A61K 31/675
30
PatentIndex Score
0
Cited by
16
References
3
Claims

Abstract

The invention relates to a compound of formula A-R—X or pharmaceutically acceptable salts thereof which can be used for producing a pharmaceutical preparation suitable for preventing or treating cancerous diseases, pathological consequences of alcohol abuse, viral hepatitis, steatohepatitis, acute and chronic pancreatitis, toxic renal diseases, hepatic insulin resistance in diabetes mellitus, hepatic damage in Wilson's disease and sideroses and/or ischaemic reperfusion damage, as an antidote against environmental toxins and medicament intoxication in order to extend the resistance time of medicaments in organisms, or for combating toxic side effects in the administration of chemotherapeutics. In the formula R is an aliphatic or aromatic C 6 - to C 40 -hydrocarbon radical which has a hydrophilic end A, and X is a radical having at least one free electron pair of a carbon or heteroatom and/or π-electrons.

Claims

exact text as granted — not AI-modified
The invention claimed is: 
     
       1. The compound 12-imidazolyl-1-dodecanol or a pharmaceutically acceptable salt thereof. 
     
     
       2. A pharmaceutical composition comprising the compound or salt thereof according to  claim 1  and a pharmaceutically acceptable carrier. 
     
     
       3. The pharmaceutical composition according to  claim 2 , which is incorporated into liposomes.

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