US8618057B2ExpiredUtilityPatentIndex 49
Anticoagulant and composition for preventing thrombus containing poly-gamma-glutamic acid
Est. expiryDec 29, 2025(expired)· nominal 20-yr term from priority
A61K 9/0095A23L 33/175A61P 7/02A61K 31/74A61K 31/195A61K 31/765
49
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Claims
Abstract
The present invention relates to an anticoagulant and a composition for preventing thrombus formation, which contain poly-gamma-glutamic acid (PGA) as an active ingredient. The inventive PGA is a water-soluble, anionic, biodegradable and edible amino acid polymer material, which has an anticoagulant effect of preventing thrombi from being accumulated in blood vessels, shows an excellent sustained-release effect and is harmless to the human body. Thus, it is useful as a high-value-added anticoagulant and a food or beverage composition for preventing thrombus formation.
Claims
exact text as granted — not AI-modifiedWhat is claimed is:
1. A method of inhibiting blood coagulation comprising administering to a patient in need thereof an anticoagulant comprising a therapeutically effective amount of poly-gamma-glutamic acid (PGA) as an active ingredient.
2. The method accord to claim 1 , wherein the molecular weight of said poly-gamma-glutamic acid (PGA) is 1-15,000 kDa.
3. A method of preventing thrombus formation comprising administering to a patient in need thereof a pharmaceutical composition comprising a therapeutically effective amount of poly-gamma-glutamic acid (PGA) as an active ingredient.
4. The method according to claim 3 , wherein the molecular weight of said poly-gamma-glutamic acid is 1-15,000 kDa.Cited by (0)
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