Apparatus, system, and method for intraocular lens power calculation using a regression formula incorporating corneal spherical aberration

Abstract

An intraocular lens, and a system and method of providing an intraocular lens, having at least one characteristic of the intraocular lens customized in accordance with a modified regression that includes a modification for corneal spherical aberration. The lens, system and method may indicate measuring at least one biometric parameter of an eye at a desired light level, determining a desired postoperative condition of the eye, obtaining a corneal spherical aberration of the eye, applying at least one empirically derived regression calculation, and predictively estimating, in accordance with an output of the at least one empirically derived regression calculation, the at least one characteristic of the intraocular lens to obtain the desired postoperative condition. The empirically derived regression calculation includes at least a product of the corneal spherical aberration with an empirically derived corneal spherical aberration constant, and a mathematical indication of the at least one biometric parameter or one of the paraxial regression formulas commonly used in clinical practice to calculate IOL power in normal patients.

What is claimed is: 
     
       1. A method of customizing a regression calculation for determining an optical power of an intraocular lens, for implantation in an eye comprising:
 measuring a biometric parameter of the eye; 
 obtaining a corneal spherical aberration of the eye; and 
 applying a modified regression formula to determine an optical power for an intraocular lens, wherein the modified regression formula is of the form:
   optical power=Regression+constant0*(corneal spherical aberration) 
   or 
   optical power=constant1*(biometric parameter)+constant0*(corneal spherical aberration) 
 
 wherein constant1 and constant0 comprise an empirically derived factor across other eyes, and wherein the Regression comprises a classical regression. 
 
     
     
       2. The method of  claim 1 , wherein the biometric parameter is selected from the group consisting of: axial length, anterior chamber depth and corneal power. 
     
     
       3. The method of  claim 1 , wherein the obtained corneal spherical aberration corresponds to the eye with a pupil at a mesopic light level. 
     
     
       4. The method of  claim 1 , wherein the obtained corneal spherical aberration corresponds to the eye with a 4 mm pupil. 
     
     
       5. The method of  claim 1 , wherein the Regression comprises one selected from at least Hoffer Q regression, Haigis regression, Holladay1 regression, Holladay2 regression, and SRK/T regression. 
     
     
       6. The method of  claim 1 , wherein said obtaining a corneal spherical aberration comprises utilizing a corneal topography. 
     
     
       7. The method of  claim 1 , wherein said obtaining a corneal spherical aberration comprises ray tracing. 
     
     
       8. The method of  claim 1 , further comprising selecting an intraocular lens in accordance with the modified regression formula. 
     
     
       9. The method of  claim 8 , further comprising implanting the selected intraocular lens. 
     
     
       10. The method of  claim 9 , further comprising:
 repeating said measuring and said obtaining after said implanting, and 
 modifying the selected intraocular lens in accordance with said repeating.