US8636987B2ActiveUtilityPatentIndex 51
Tooth whitening compositions and methods
Est. expiryJul 15, 2028(~2 yrs left)· nominal 20-yr term from priority
A61P 31/02A61P 31/10A61P 31/04A61P 1/02A61P 17/02A61P 17/16A61P 17/00A61Q 11/00A61K 8/8147A61K 8/731A61K 8/20C01B 11/024A61K 8/23
51
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Cited by
173
References
10
Claims
Abstract
A method of whitening a tooth surface including contacting the surface of a tooth with an efficacious amount of a substantially non-cytotoxic composition. The non-cytotoxic composition includes chlorine dioxide and no more than about 0.25 milligrams oxy-chlorine anions per gram of the composition.
Claims
exact text as granted — not AI-modifiedWhat is claimed is:
1. A method of whitening a tooth surface, the method comprising contacting the surface of a tooth with an efficacious amount of a substantially non-cytotoxic composition, wherein the composition comprises oxy-chlorine anions, at least about 20 ppm chlorine dioxide and no more than about 0.25 milligrams oxy-chlorine anion per gram of the composition.
2. The method of claim 1 , wherein the composition comprises about 20 to about 1000 ppm chlorine dioxide.
3. The method of claim 1 , wherein the composition comprises less than about 0.2 milligrams oxy-chlorine anion per gram composition.
4. The method of claim 1 , wherein the composition has a pH from about 4.5 to about 11.
5. The method of claim 1 , wherein the composition is a thickened fluid composition comprising a thickener component.
6. The method of claim 5 , wherein the thickener component is selected from the group consisting of natural hydrocolloids, semisynthetic hydrocolloids, synthetic hydrocolloids, and clay.
7. The method of claim 1 , wherein contacting the tooth with the composition does not: substantially damage hard tooth tissue; substantially reduce enamel microhardness; substantially reduce dentin microhardness; cause tooth sensitivity and/or substantially increase surface roughness of at least one of enamel and dentin.
8. The method of claim 7 , wherein rate and/or extent of rebound is reduced compared to a peroxide bleaching agent.
9. The method of claim 1 , wherein the composition is substantially non-irritating and contacting the tooth surface includes substantial contact with soft oral tissue.
10. The method of claim 1 , wherein the contacted tooth surface is whitened by at least about 3 shade value units.Cited by (0)
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