US9308206B2ExpiredUtilityA1

Compositions and methods for treating colon cancer

54
Individually held — no corporate assignee on recordPriority: Aug 23, 2004Filed: Jan 27, 2014Granted: Apr 12, 2016
Est. expiryAug 23, 2024(expired)· nominal 20-yr term from priority
Inventors:Satish K. SrivastavaKota V. Ramana
G01N 33/57535A61K 31/195A61K 31/517C12Q 1/26G01N 33/5735G01N 33/57419C12N 2310/14C12Y 101/01021A61K 31/426G01N 2500/00A61K 31/502C12N 15/1137A61K 31/4188A61K 31/4747
54
PatentIndex Score
0
Cited by
10
References
1
Claims

Abstract

Certain embodiments are directed to methods of treating a pathophysiological state or symptoms thereof resulting from aldose reductase-mediated signaling in a cytotoxic pathway using an aldose reductase specific inhibitor.

Claims

exact text as granted — not AI-modified
The invention claimed is: 
     
       1. A method of inhibiting colon cancer cell proliferation in a subject having colon cancer which consists of administering a pharmacologically effective amount of fidarestat which is a specific inhibitor of aldose reductase to the subject having colon cancer, wherein colon cancer cell proliferation in said subject is inhibited.

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