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US9364428B2ExpiredUtilityPatentIndex 37

Herb medicine composition in the form of jelly

Assignee: FUKUCHI TSUNEHIROPriority: Jul 29, 2002Filed: Jul 28, 2003Granted: Jun 14, 2016
Est. expiryJul 29, 2022(expired)· nominal 20-yr term from priority
Inventors:FUKUCHI TSUNEHIROMATSUURA KOJITATSUMI NOBORUDAIRAKU MASATAKETOGASHI MITSUO
A61K 36/232A61K 36/48A61P 11/00A61K 47/36A61K 36/8945A61K 9/0056A61K 36/40A61K 9/06A61K 36/884A61K 36/714A61K 36/65A61K 36/54A61K 36/736A61K 36/64A61K 36/07A61K 36/00A61K 9/00
37
PatentIndex Score
0
Cited by
30
References
19
Claims

Abstract

A Chinese herbal medical composition in the form of jelly, wherein a Chinese herbal medicine is contained in a base containing at least one substance selected from the group consisting of carrageenan, carob bean gum and xanthan gum and not containing phosphate buffer. The Chinese herbal medical composition hardly causes syneresis, is superior in the preservative stability, is broadly applicable to a Chinese herbal medicine and is orally taken without taking care of the bitter of a Chinese herbal medicine.

Claims

exact text as granted — not AI-modified
The invention claimed is: 
     
       1. A Chinese herbal medical composition in the form of jelly, consisting of a Chinese herbal medicine in a base,
 wherein the Chinese herbal medicine is selected from the group consisting of Kakkon-to and Sho-saiko-to, and is present in an amount from 14 w/w % to less than 60 w/w % per total amount of the composition, 
 wherein the base consists of 0.01 to 10.0 w/w % carrageenan, 0.01 to 10.0 w/w % carob bean gum, 0.01 to 10.0 w/w % xanthan gum, per total amount of the composition, and at least one pharmaceutically acceptable additive selected from the group consisting of a stabilizing agent, a corrective agent, an emulsifying agent, a dispersion agent, a sweetening agent, a flavoring agent, a coloring agent, and a preservative, 
 wherein the carrageenan is iota carrageenan alone, and 
 wherein the base does not include a phosphate buffer or agar. 
 
     
     
       2. The Chinese herbal medical composition according to  claim 1 ,
 wherein the Chinese herbal medicine is present in an amount less than 30 w/w % per total amount of the composition, and 
 wherein the base consists of 0.08 to 2.0 w/w % carrageenan, 0.1 to 2.0 w/w % carob bean gum, and 0.08 to 2.0 w/w % xanthan gum, per total amount of the composition, and at least one pharmaceutically acceptable additive selected from the group consisting of a stabilizing agent, a corrective agent, an emulsifying agent, a dispersion agent, a sweetening agent, a flavoring agent, a coloring agent, and a preservative. 
 
     
     
       3. The Chinese herbal medical composition according to  claim 1 , wherein the amount of the Chinese herbal medicine is 14 to 30 w/w % per total amount of the composition. 
     
     
       4. A process for preparing the Chinese herbal medical composition according to  claim 1 , comprising:
 mixing the Kakkon-to or Sho-saiko-to with the carrageenan, the carob bean gum, the xanthan gum, and the at least one pharmaceutically acceptable additive, and 
 then adding warm water to the mixture or adding water to the mixture and further warming it, 
 wherein the resulting composition is stable. 
 
     
     
       5. The Chinese herbal medical composition according to  claim 1 ,
 wherein the Chinese herbal medicine is present in an amount less than 50 w/w % per total amount of the composition, and 
 wherein the base consists of 0.05 to 5.0 w/w % carrageenan, 0.05 to 5.0 w/w % carob bean gum, and 0.05 to 5.0 w/w % xanthan gum, per total amount of the composition, and at least one pharmaceutically acceptable additive selected from the group consisting of a stabilizing agent, a corrective agent, an emulsifying agent, a dispersion agent, a sweetening agent, a flavoring agent, a coloring agent, and a preservative. 
 
     
     
       6. The Chinese herbal medical composition according to  claim 1 , wherein the Chinese herbal medicine is Kakkon-to, and is present in an amount of 30 w/w % per total amount of the composition. 
     
     
       7. The Chinese herbal medical composition according to  claim 1 , wherein the Chinese herbal medicine is Kakkon-to, and is present in an amount of 15 w/w % per total amount of the composition. 
     
     
       8. The Chinese herbal medical composition according to  claim 2 , wherein the Chinese herbal medicine is Kakkon-to, and is present in an amount of 15 w/w % per total amount of the composition. 
     
     
       9. The Chinese herbal medical composition according to  claim 6 ,
 wherein the base consists of 0.5 w/w % carrageenan, 0.1 w/w % carob bean gum, and 0.2 w/w % xanthan gum, per total amount of the composition, and at least one pharmaceutically acceptable additive selected from the group consisting of a stabilizing agent, a corrective agent, an emulsifying agent, a dispersion agent, a sweetening agent, a flavoring agent, a coloring agent, and a preservative. 
 
     
     
       10. The Chinese herbal medical composition according to  claim 9 ,
 wherein the at least one pharmaceutically acceptable additive present in the base are 0.02 w/w % propyl parahydroxybenzoate and 69.18 w/w % water, per total amount of the composition. 
 
     
     
       11. The Chinese herbal medical composition according to  claim 7 ,
 wherein the base consists of 1 w/w % carrageenan, 0.25 w/w % carob bean gum, and 0.45 w/w % xanthan gum, per total amount of the composition, and at least one pharmaceutically acceptable additive selected from the group consisting of a stabilizing agent, a corrective agent, an emulsifying agent, a dispersion agent, a sweetening agent, a flavoring agent, a coloring agent, and a preservative. 
 
     
     
       12. The Chinese herbal medical composition according to  claim 11 ,
 wherein the at least one pharmaceutically acceptable additive present in the base are at least one sweetening agent, at least one dispersion agent, and at least one preservative. 
 
     
     
       13. The Chinese herbal medical composition according to  claim 12 , wherein:
 the at least one sweetening agent is selected from the group consisting of glucose, fructose, saccharin sodium, sucrose, D-sorbitol, D-mannitol, and hydrogenated maltose starch syrup, 
 the at least one dispersion agent is selected from the group consisting of glycerin, propylene glycol and water, and 
 the preservative is propyl parahydroxybenzoate. 
 
     
     
       14. The Chinese herbal medical composition according to  claim 11 ,
 wherein the at least one pharmaceutically acceptable additive present in the base are 6 w/w % hydrogenated maltose starch syrup, 6 w/w % D-sorbitol, 6 w/w % glycerin, 1 w/w % propylene glycol, 0.02 w/w % propyl parahydroxybenzoate and 64.28 w/w % water, per total amount of the composition. 
 
     
     
       15. The Chinese herbal medical composition according to  claim 2 ,
 wherein the at least one pharmaceutically acceptable additive present in the base are at least one sweetening agent, at least one dispersion agent, and at least one preservative. 
 
     
     
       16. The Chinese herbal medical composition according to  claim 15 , wherein:
 the at least one sweetening agent is selected from the group consisting of glucose, fructose, saccharin sodium, sucrose, D-sorbitol, D-mannitol, and hydrogenated maltose starch syrup, 
 the at least one dispersion agent is selected from the group consisting of glycerin, propylene glycol and water, and 
 the preservative is propyl parahydroxybenzoate. 
 
     
     
       17. The Chinese herbal medical composition according to  claim 7 ,
 wherein the at least one pharmaceutically acceptable additive present in the base are at least one sweetening agent, at least one dispersion agent, and at least one preservative. 
 
     
     
       18. The Chinese herbal medical composition according to  claim 17 , wherein:
 the at least one sweetening agent is selected from the group consisting of glucose, fructose, saccharin sodium, sucrose, D-sorbitol, D-mannitol, and hydrogenated maltose starch syrup, 
 the at least one dispersion agent is selected from the group consisting of glycerin, propylene glycol and water, and 
 the preservative is propyl parahydroxybenzoate. 
 
     
     
       19. The Chinese herbal medical composition according to  claim 1 , wherein the sweetening agent is at least one selected from the group consisting of glucose, fructose, saccharin sodium, sucrose, D-sorbitol, D-mannitol, and hydrogenated maltose starch syrup.

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