Anhydrous hydrogel composition and delivery system

Abstract

The present disclosure relates to anhydrous hydrogels useful as mucoadhesive (oral compositions) or as topical agents and may be used to deliver an active agent such as active pharmaceutical agents (API's), coagulants, fragrances, flavors, and other actives and excipients.

The invention claimed is: 
     
       1. An anhydrous hydrogel product obtained by the process of combining from 5-30% by weight NaCMC with minimal residual water, 95-70% by weight anhydrous glycerin containing 0.5% or lower residual water, 0.1-30% by weight dehydrated active agent, and followed by the addition of an energy source. 
     
     
       2. An anhydrous hydrogel obtained by the process of combining wherein said anhydrous hydrogel comprises from 10-20% by weight NaCMC with minimal residual water, 90-80% by weight anhydrous glycerin containing 0.5% or lower residual water, 0.1-30% by weight dehydrated active agent, and followed by the addition of an energy source. 
     
     
       3. An anhydrous hydrogel obtained by the process of combining from 14-16% by weight NaCMC with minimal residual water, 86-84% by weight anhydrous glycerin containing 0.5% or lower residual water, 0.1-30% by weight dehydrated active agent, and followed by the addition of an energy source. 
     
     
       4. An anhydrous hydrogel product according to  claim 1  wherein the energy source is heat or radiation. 
     
     
       5. An anhydrous hydrogel product according to  claim 2  wherein the energy source is heat or radiation. 
     
     
       6. An anhydrous hydrogel product according to  claim 3  wherein the energy source is heat or radiation.