Dicarboxylic acid compound

Abstract

It is an object of the present invention to provide a medicament for preventing or treating hyperphosphatemia. Solution: A compound represented by a general formula (I) or a pharmacologically acceptable salt thereof. (In the formula, R 1 : a methyl group or the like, R 2 : a hydrogen atom or the like, R 3 : a hydrogen atom or the like, A: a cyclohexyl ring or the like, X: CH or the like, Y: CH or the like, Z: CH or the like, and n: 2 or the like).

The invention claimed is: 
     
       1. A compound of the following formula: 
       
         
           
           
               
               
           
         
       
       or a pharmacologically acceptable salt thereof, or a hydrate of the compound or pharmacologically acceptable salt thereof. 
     
     
       2. The compound of  claim 1  wherein the pharmacologically acceptable salt is a disodium salt. 
     
     
       3. The compound of  claim 1  wherein the hydrate of the compound is the trihydrate. 
     
     
       4. A compound of the following formula: 
       
         
           
           
               
               
           
         
       
     
     
       5. A method for the prevention or treatment of hyperphosphatemia comprising administering to a patient a compound according to  claim 4 . 
     
     
       6. A pharmaceutical composition comprising the compound according to  claim 4 . 
     
     
       7. The pharmaceutical composition according to  claim 6 , wherein administration of an effective amount of the pharmaceutical composition to a patient inhibits the uptake of phosphorus in the patient. 
     
     
       8. A method for the prevention or treatment of hyperphosphatemia comprising administering to a patient a compound or pharmacologically acceptable salt thereof, or the hydrate of the compound or pharmacologically acceptable salt thereof, according to  claim 1 . 
     
     
       9. A pharmaceutical composition comprising the compound or pharmacologically acceptable salt thereof, or the hydrate of the compound or pharmacologically acceptable salt thereof, according to  claim 1 . 
     
     
       10. The pharmaceutical composition according to  claim 9 , wherein administration of an effective amount of the pharmaceutical composition to a patient inhibits the uptake of phosphorus in the patient.