Organic compounds

Abstract

The invention relates to compounds and methods of treatment relating to nicotinic receptor antagonists. For example, the compounds and methods of treatment function block the activity of certain acetylcholine receptors and subtypes therein, and are useful treating diseases and conditions mediated by nicotinic receptor stimulation, e.g., small cell lung cancer.

The invention claimed is: 
     
       1. A pharmaceutical composition comprising a compound as follows: 
       
         
           
           
               
               
           
         
         in free or pharmaceutically acceptable salt form; wherein the compound is in an admixture with a pharmaceutically acceptable diluent or carrier. 
       
     
     
       2. The pharmaceutical composition according to  claim 1 , wherein the compound binds to the nicotinic acetylcholine receptor with a high affinity, preferably less than 1 nM.